Article
A novel approach - the propensity to propagate (PTP) method for controlling for host factors in studying the transmission of Mycobacterium tuberculosis.
PloS one - 1 Jan 2014
Nebenzahl-Guimaraes Hanna, Borgdorff Martien W, Murray Megan B, van Soolingen Dick
Abstract excerpt
RATIONALE: Understanding the genetic variations among Mycobacterium tuberculosis (MTB) strains with differential ability to transmit would be a major step forward in preventing transmission. OBJECTIVES: To describe a method to extend conventional proxy measures of transmissibility by adjusting for patient-related factors, thus strengthening the causal association found with bacterial factors. METHODS: Clinical,...
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