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Caenorhabditis elegans as an In Vivo Model Organism to Elucidate Teratogenic Effects.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Wang Zhenglu

Abstract excerpt

Exogenous teratogens contribute to approximately 10% of the human abnormality with exposure occurrence during the prenatal and fetal period. However, the assessment methods and underlying mechanism remain unclear. The nematode Caenorhabditis elegans has been recognized as one of the ideal model animals for toxicologic research as convenient culture, low cost, and complete phenotypes and genomic profiling. This...

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PMID: 38285345
DOI: 10.1007/978-1-0716-3625-1_14

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