Article
Establishment of culture systems for Genotypes 3 and 4 hepatitis E virus (HEV) obtained from human blood and application of HEV inactivation using a pathogen reduction technology system.
Transfusion - 1 Nov 2014
Owada Takashi, Kaneko Moe, Matsumoto Chieko, Sobata Rieko, Igarashi Masashi, Suzuki Ko, Matsubayashi Keiji, Mio Kazuhiro, Uchida Shigeharu, Satake Masahiro, Tadokoro Kenji
Abstract excerpt
BACKGROUND: It has been demonstrated that the hepatitis E virus (HEV) can be transmitted via blood transfusion, and the risk of HEV transmission via transfusion has become a major global concern. An HEV culture system for blood-derived HEV has been sought to obtain valuable knowledge of the virus and the risk of HEV infection through blood products. STUDY DESIGN AND METHODS: We endeavored to establish an HEV...
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