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Article

Low hepatitis E virus RNA prevalence in a large-scale survey of United States source plasma donors.

Transfusion - 1 Dec 2017

Roth Nathan J, Schäfer Wolfram, Alexander Rick, Elliott Kevin, Elliott-Browne Wlenyeno, Knowles Jonathan, Wenzel Jürgen J, Simon Toby L

Abstract excerpt

BACKGROUND: Hepatitis E virus (HEV) is a small, nonenveloped, single-stranded, RNA virus of emerging concern in industrialized countries. HEV transmission through transfusion of blood components has been reported, but not via plasma-derived medicinal products (PDMPs) manufactured with virus inactivation and/or removal steps. This study aimed to determine the prevalence of HEV among US source plasma donors. STUDY...

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Identifiers

PMID: 28833188
DOI: 10.1111/trf.14285

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