Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.

doi:10.1007/s00401-014-1285-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.

Acta neuropathologica - 1 Jul 2014

de Kock Leanne, Sabbaghian Nelly, Plourde François, Srivastava Archana, Weber Evan, Bouron-Dal Soglio Dorothée, Hamel Nancy, Choi Joon Hyuk, Park Sung-Hye, Deal Cheri L, Kelsey Megan M, Dishop Megan K, Esbenshade Adam, Kuttesch John F, Jacques Thomas S, Perry Arie, Leichter Heinz, Maeder Philippe, Brundler Marie-Anne, Warner Justin, Neal James, Zacharin Margaret, Korbonits Márta, Cole Trevor, Traunecker Heidi, McLean Thomas W, Rotondo Fabio, Lepage Pierre, Albrecht Steffen, Horvath Eva, Kovacs Kalman, Priest John R, Foulkes William D

Abstract excerpt

Individuals harboring germ-line DICER1 mutations are predisposed to a rare cancer syndrome, the DICER1 Syndrome or pleuropulmonary blastoma-familial tumor and dysplasia syndrome [online Mendelian inheritance in man (OMIM) #601200]. In addition, specific somatic mutations in the DICER1 RNase III c...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatal Outcome

Share to Germ-Line Mutation

Share to Magnetic Resonance Imaging

Share to Pituitary Neoplasms

Share to Radiography, Thoracic

Share to Ribonuclease III

Share to Tomography, X-Ray Computed

Source

Open in PubMed Open full text

Identifiers

PMID: 24839956
DOI: 10.1007/s00401-014-1285-z
PMCID: PMC4129448

Genes

DICER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24839956-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.PMID 24839956Read ↗

Molecular characterization of DICER1-mutated pituitary blastoma.Semantic proximity Read ↗

Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma.Semantic proximity Read ↗

DICER1-Pleuropulmonary Blastoma Familial Tumor Predisposition SyndromeSemantic proximity Read ↗

DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome.Semantic proximity Read ↗

Germline and Somatic<i>DICER1</i>Mutations in a Pituitary Blastoma Causing Infantile-Onset Cushing's DiseaseSemantic proximity Read ↗

DICER1 Syndrome and Cancer Predisposition: From a Rare Pediatric Tumor to Lifetime RiskSemantic proximity Read ↗

Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastomaSemantic proximity Read ↗

DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.Semantic proximity Read ↗

Temporal order of RNase IIIb and loss-of-function mutations during development determines phenotype in pleuropulmonary blastoma / DICER1 syndrome: a unique variant of the two-hit tumor suppression modelSemantic proximity Read ↗

Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigreeSemantic proximity Read ↗

Pleuropulmonary blastoma and DICER1-related tumor predisposition: from clinicopathologic observations to clinical trial.Semantic proximity Read ↗

DICER1 syndrome in a young adult with pituitary blastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.