Article
Benzyl alcohol alters the hemoglobin phenotype of mouse erythroleukemia cells.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Scher W, Scher B M, Hellinger N, Waxman S
Abstract excerpt
The hemoglobin minor/hemoglobin major ratio expressed in mouse erythroleukemia (MEL) cells grown in vitro varies according to the differentiation inducer utilized. For example, butyrate and hemin induce higher hemoglobin minor/hemoglobin major ratios than do dimethyl sulfoxide (DMSO) or hexamethylene bisacetamide (HMBA). Benzyl alcohol in non-toxic concentrations was found to markedly reduce the hemoglobin...
Topics
- Acetamides
- Animals
- Aprotinin
- Benzyl Alcohol
- Benzyl Alcohols
- Benzyl Compounds
- Cell Differentiation
- Dexamethasone
- Dimethyl Sulfoxide
- Hemoglobins
- Leukemia, Erythroblastic, Acute