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Comprehensive analysis of blood group antigen binding to classical and El Tor cholera toxin B-pentamers by NMR

14 May 2014

Abstract excerpt

Cholera is a diarrheal disease responsible for the deaths of thousands, possibly even hundreds of thousands of people every year, and its impact is predicted to further increase with climate change. It has been known for decades that blood group O individuals suffer more severe symptoms of cholera compared with individuals with other blood groups (A, B and AB). The observed blood group dependence is likely to be...

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PMID: 24829308
DOI: 10.1093/glycob/cwu040

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