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Article

Towards the identification of a genetic basis for Landau-Kleffner syndrome.

Epilepsia - 1 Jun 2014

Conroy Judith, McGettigan Paul A, McCreary Dara, Shah Naisha, Collins Kevin, Parry-Fielder Bronwyn, Moran Margaret, Hanrahan Donncha, Deonna Thierry W, Korff Christian M, Webb David, Ennis Sean, Lynch Sally A, King Mary D

Abstract excerpt

OBJECTIVE: To establish the genetic basis of Landau-Kleffner syndrome (LKS) in a cohort of two discordant monozygotic (MZ) twin pairs and 11 isolated cases. METHODS: We used a multifaceted approach to identify genetic risk factors for LKS. Array comparative genomic hybridization (CGH) was performed using the Agilent 180K array. Whole genome methylation profiling was undertaken in the two discordant twin pairs,...

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Cell Adhesion Molecules
Cell Adhesion Molecules, Neuronal
Comparative Genomic Hybridization
Extracellular Matrix Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, N-Methyl-D-Aspartate

Serine Endopeptidases

Twins, Monozygotic

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Identifiers

PMID: 24828792
DOI: 10.1111/epi.12645

Genes

BSN
EPHB2
NID2
RELN

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