Article
Association of ESR1 gene polymorphism with preterm rupture of fetal membranes.
Bulletin of experimental biology and medicine - 1 Apr 2014
Kan N E, Tyutyunnik V L, Donnikov A E, Sannikova M V, Sukhikh G T
Abstract excerpt
We examined 179 patients with and without preterm rupture of fetal membranes. The mothers and their newborns have been genotyped by two polymorphic loci of estrogen receptor α (ESR1) gene: -397T > C[PvuII] (rs2234693) and -351A > G[XbaI] (rs9340799). The CG haplotype of the fetus should be regarded as a risk factor of preterm rupture of fetal membranes, while haplotype TA as a protective factor. Genotype -351A/A...
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