Article
Epidemiology and pathogenesis of otitis media: construction of a phenotype landscape.
Audiology & neuro-otology - 1 Jan 2014
Bhutta Mahmood F
Abstract excerpt
Otitis media (OM) represents a complex set of clinically defined disease phenotypes. Epidemiological and pathological data suggest that inflammation of the middle ear occurs on a continuum of disease. Here I review epidemiological data and apply mathematical modelling to better define the interrelation of OM phenotypes, including the relationship of upper respiratory tract infection to acute OM (AOM), of AOM to...
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