Article
Comparison between an in-house method and the ViroSeq™ method for determining mutations for drug resistance in the HIV-1 CRF01_AE subtype circulating in China.
Journal of virological methods - 1 Sept 2014
Li Hanping, Liang Shujia, Guo Wei, Zhuang Daomin, Li Lin, Liu Yongjian, Bao Zuoyi, Liu Siyang, Wang Xiaolin, Li Tianyi, Liu Wei, Li Jingyun
Abstract excerpt
Commercial products for determining the drug-resistance mutations of HIV-1 are expensive and usually focus on a particular HIV-1 subtype. In this study, a more cost-effective in-house method was compared side-by-side with the ViroSeq™ Genotyping System 2.0 for determining resistant mutations in China's most prevalent subtype, CRF01_AE. Plasma samples were obtained from 205 patients infected with HIV-1, and...
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