Article
Age and CGG-repeat length are associated with neuromotor impairments in at-risk females with the FMR1 premutation.
Neurobiology of aging - 1 Sept 2014
Kraan Claudine M, Hocking Darren R, Georgiou-Karistianis Nellie, Metcalfe Sylvia A, Archibald Alison D, Fielding Joanne, Trollor Julian, Bradshaw John L, Cohen Jonathan, Cornish Kim M
Abstract excerpt
Recent studies report a higher risk of dementia and motor symptoms in females with the fragile X mental retardation 1 premutation (PM-carriers) than has hitherto been appreciated. Here, we use dual-task gait paradigms to identify potential markers of cognitive and motor decline in female PM-carriers. Spatiotemporal gait characteristics and variability of gait were assessed during single- and dual-task conditions...
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