Article
[The epigenome in neurological disorders: a new marker for understanding neuronal dysfunction].
Brain and nerve = Shinkei kenkyu no shinpo - 1 May 2014
Kubota Takeo, Hirasawa Takae, Miyake Kunio
Abstract excerpt
An epigenome is a chemical modification pattern of genomic DNA that determines the on/off status of genes, and its abnormalities are known to cause congenital diseases. Recent studies have shown that epigenomic patterns are altered by various environmental factors, indicating that epigenomic abnormalities also cause acquired mental and neurological diseases. An epigenomic pattern that reflects past environmental...
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