Article
Recent host range expansion of canine distemper virus and variation in its receptor, the signaling lymphocyte activation molecule, in carnivores.
Journal of wildlife diseases - 1 Jul 2014
Ohishi Kazue, Suzuki Rintaro, Maeda Taro, Tsuda Miwako, Abe Erika, Yoshida Takao, Endo Yasuyuki, Okamura Maki, Nagamine Takashi, Yamamoto Hanae, Ueda Miya, Maruyama Tadashi
Abstract excerpt
The signaling lymphocyte activation molecule (SLAM) is a receptor for morbilliviruses. To understand the recent host range expansion of canine distemper virus (CDV) in carnivores, we determined the nucleotide sequences of SLAMs of various carnivores and generated three-dimensional homology SLAM models. Thirty-four amino acid residues were found for the candidates binding to CDV on the interface of the carnivore...
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