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Animal morbilliviruses and their cross-species transmission potential

1 Apr 2020

Abstract excerpt

Like measles virus (MV), whose primary hosts are humans, non-human animal morbilliviruses use SLAM (signaling lymphocytic activation molecule) and PVRL4 (nectin-4) expressed on immune and epithelial cells, respectively, as receptors. PVRL4's amino acid sequence is highly conserved across species, while that of SLAM varies significantly. However, non-host animal SLAMs often function as receptors for different...

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PMID: 32344228
DOI: 10.1016/j.coviro.2020.03.005

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