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Article

FGFR1 mutations in Rosette-forming glioneuronal tumors of the fourth ventricle.

Journal of neuropathology and experimental neurology - 1 Jun 2014

Gessi Marco, Moneim Yasmin Abdel, Hammes Jennifer, Goschzik Tobias, Scholz Martin, Denkhaus Dorota, Waha Andreas, Pietsch Torsten

Abstract excerpt

Rosette-forming glioneuronal tumors (RGNTs) are rare glioneuronal tumors of the fourth ventricle region that preferentially affect young adults. Despite their histologic similarity with pilocytic astrocytomas (PAs), RGNTs do not harbor KIAA1549-BRAF fusions or BRAF mutations, which represent the most common genetic alteration in PAs. Recently, mutations affecting the hotspot codons Asn546 and Lys656 of fibroblast...

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Source

Identifiers

PMID: 24806303
DOI: 10.1097/NEN.0000000000000080

Genes

FGFR1
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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