Article
The genotype of the transporter associated with antigen processing gene affects susceptibility to colorectal cancer in Japanese.
Environmental health and preventive medicine - 1 Jul 2014
Yamauchi Takenori, Takeuchi Shouhei, Maehara Naoki, Kuroda Yoshiki
Abstract excerpt
OBJECTIVE: Although colorectal cancer (CRC) is one of the most frequent malignancies in Japan, the associated genetic factors remain to be elucidated. Functional loss of the transporter associated with antigen processing (TAP) 1 gene induces carcinogenesis. We investigated whether single nucleotide polymorphisms (SNPs) in the TAP1 gene (rs735883) are associated with susceptibility to CRC in a Japanese population....
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