Article
Influence of mosquito genotype on transcriptional response to dengue virus infection.
Functional & integrative genomics - 1 Sept 2014
Behura Susanta K, Gomez-Machorro Consuelo, deBruyn Becky, Lovin Diane D, Harker Brent W, Romero-Severson Jeanne, Mori Akio, Severson David W
Abstract excerpt
The mosquito Aedes aegypti is the principal vector that transmits dengue virus (DENV) to humans. The primary factors that trigger a susceptible or refractory interaction of A. aegypti with DENV are not well understood. In this study, our aim is to characterize the influence of vector genotype on differential gene expression of susceptible vs. refractory A. aegypti strains to DENV infection. To accomplish that, we...
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