Molecular mechanisms of ageing and related diseases

Abstract excerpt

Human and other multicellular life species age, and ageing processes become dominant during the late phase of life. Recent studies challenge this dogma, suggesting that ageing does not occur in some animal species. In mammals, cell replicative senescence occurs as early as before birth (i.e. in embryos) under physiological conditions. How the molecular machinery operates and why ageing cells dominate under some...

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• Share to Genetics, Aging, and Longevity in Model Organisms
• Share to Mitochondrial Function and Pathology
• Share to Telomeres, Telomerase, and Senescence