Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A population of progenitor cells in the basal and intermediate layers of the murine bladder urothelium contributes to urothelial development and regeneration

5 May 2014

Abstract excerpt

BACKGROUND: Homeostatic maintenance and repair of the bladder urothelium has been attributed to proliferation of keratin 5-expressing basal cells (K5-BC) with subsequent differentiation into superficial cells. Recent evidence, however, suggests that the intermediate cell layer harbors a population of progenitor cells. We use label-retaining cell (LRC) methodology in conjunction with a clinically relevant model of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Tissue Engineering and Regenerative Medicine
Share to Urinary Bladder and Prostate Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24796293
DOI: 10.1002/dvdy.24143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A population of progenitor cells in the basal and intermediate layers of the murine bladder urothelium contributes to urothelial development and regenerationPMID 24796293Read ↗

Urothelial proliferation and regeneration after spinal cord injury.Semantic proximity Read ↗

Stem cells in the biology of normal urothelium and urothelial carcinomaSemantic proximity Read ↗

Single‐cell transcriptomes of mouse bladder urothelium uncover novel cell type markers and urothelial differentiation characteristicsSemantic proximity Read ↗

Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and EndoreplicationSemantic proximity Read ↗

Differentiation potential of urothelium from patients with benign bladder dysfunctionSemantic proximity Read ↗

Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates the Development of Basal Squamous-Like Invasive Bladder Cancer in the Chemical Carcinogenesis of Mouse Bladder.Semantic proximity Read ↗

Generation of Bladder Urothelium from Human Pluripotent Stem Cells under Chemically Defined Serum- and Feeder-Free SystemSemantic proximity Read ↗

The human urothelium consists of multiple clonal units, each maintained by a stem cellSemantic proximity Read ↗

Clonal, Self-Renewing and Differentiating Human and Porcine Urothelial Cells, a Novel Stem Cell PopulationSemantic proximity Read ↗

p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia.Semantic proximity Read ↗

Plasticity of the urothelial phenotype: effects of gastrointestinal mesenchyme/stroma and implications for urinary tract reconstruction.Semantic proximity Read ↗

Assessing the differentiation state of cultured bovine urothelial cells: elevated synthesis of stratification-related K5 and K6 keratins and persistent expression of uroplakin I.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.