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Article

Homozygous deletion of six genes including corneodesmosin on chromosome 6p21.3 is associated with generalized peeling skin disease.

Journal of dermatological science - 1 Jul 2014

Teye Kwesi, Hamada Takahiro, Krol Rafal P, Numata Sanae, Ishii Norito, Matsuda Mitsuhiro, Ohata Chika, Furumura Minao, Hashimoto Takashi

Abstract excerpt

BACKGROUND: Peeling skin syndrome (PSS) is a rare autosomal recessive form of ichthyosis showing skin exfoliation. PSS is divided into acral and generalized PSS, and the latter is further classified into non-inflammatory type (PSS type A) and inflammatory type (PSS type B). PSS type B is now called peeling skin disease (PSD). Different loss-of-function mutations in the corneodesmosin (CDSN) gene have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24794518
DOI: 10.1016/j.jdermsci.2014.04.003

Genes

CDSN
PSD
CCHCR1
TCF19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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