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Article

Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

30 Apr 2014

Abstract excerpt

BACKGROUND: Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (HIV). METHODS: The study population comprised prospective cohorts of children who were undergoing evaluation for...

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PMID: 24785206
DOI: 10.1056/nejmoa1303657

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