Article
Geographic population structure analysis of worldwide human populations infers their biogeographical origins.
Nature communications - 29 Apr 2014
Elhaik Eran, Tatarinova Tatiana, Chebotarev Dmitri, Piras Ignazio S, Maria Calò Carla, De Montis Antonella, Atzori Manuela, Marini Monica, Tofanelli Sergio, Francalacci Paolo, Pagani Luca, Tyler-Smith Chris, Xue Yali, Cucca Francesco, Schurr Theodore G, Gaieski Jill B, Melendez Carlalynne, Vilar Miguel G, Owings Amanda C, Gómez Rocío, Fujita Ricardo, Santos Fabrício R, Comas David, Balanovsky Oleg, Balanovska Elena, Zalloua Pierre, Soodyall Himla, Pitchappan Ramasamy, Ganeshprasad Arunkumar, Hammer Michael, Matisoo-Smith Lisa, Wells R Spencer
Abstract excerpt
The search for a method that utilizes biological information to predict humans' place of origin has occupied scientists for millennia. Over the past four decades, scientists have employed genetic data in an effort to achieve this goal but with limited success. While biogeographical algorithms using next-generation sequencing data have achieved an accuracy of 700 km in Europe, they were inaccurate elsewhere. Here...
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