Article
SARS-CoV envelope protein palmitoylation or nucleocapid association is not required for promoting virus-like particle production
27 Apr 2014
Abstract excerpt
BACKGROUND: Coronavirus membrane (M) proteins are capable of interacting with nucleocapsid (N) and envelope (E) proteins. Severe acute respiratory syndrome coronavirus (SARS-CoV) M co-expression with either N or E is sufficient for producing virus-like particles (VLPs), although at a lower level compared to M, N and E co-expression. Whether E can release from cells or E/N interaction exists so as to contribute to...
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