Article
VIM proteins regulate transcription exclusively through the MET1 cytosine methylation pathway.
Epigenetics - 1 Jul 2014
Shook Molly S, Richards Eric J
Abstract excerpt
In Arabidopsis, variant in methylation (VIM) proteins are required for the maintenance of DNA methylation in the CpG dinucleotide context. VIM1 acts as a cofactor of DNA methyltransferase 1 (MET1), although the mechanism for this co-regulation remains unclear. In this study, we used RNA-seq analysis to profile the transcriptomes of vim1, vim1 vim2 vim3, and met1 null mutants. Consistent with previous studies...
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