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Article

Distribution and haplotype associations of XPD Lys751Gln, XRCC1 Arg280His and XRCC1 Arg399Gln polymorphisms with nasopharyngeal carcinoma in the Malaysian population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Visuvanathan Shaneeta, Chong Pei-Pei, Yap Yoke-Yeow, Lim Chin-Chye, Tan Meng-Kuan, Lye Munn-Sann

Abstract excerpt

BACKGROUND: DNA repair pathways play a crucial role in maintaining the human genome. Previous studies associated DNA repair gene polymorphisms (XPD Lys751Gln, XRCC1 Arg280His and XRCC1 Arg399Gln) with nasopharyngeal carcinoma. These non-synonymous polymorphisms may alter DNA repair capacity and thus increase or decrease susceptibility. The present study aimed to determine the genotype distribution of XPD codon...

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Identifiers

PMID: 24761895
DOI: 10.7314/apjcp.2014.15.6.2747

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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