Article
Fluoxetine prevents dystrophic changes in a zebrafish model of Duchenne muscular dystrophy.
Human molecular genetics - 1 Sept 2014
Waugh Trent A, Horstick Eric, Hur Junguk, Jackson Samuel W, Davidson Ann E, Li Xingli, Dowling James J
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a common and relentlessly progressive muscle disease. Some interventions have been identified that modestly slow progression and prolong survival, but more meaningful therapies are lacking. The goal of this study is to identify new therapeutic pathways for DMD using a zebrafish model of the disease. To accomplish this, we performed a non-biased drug screen in sapje, a...
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