Article
Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma.
Tissue antigens - 1 Sept 2014
Xie H-Y, Xing C-Y, Wei B-J, Xu X, Wu J, Chen L-M, Cao G-Q, Chen H, Chen K-J, Yin S-Y, Wu L-M, Zhou L, Zheng S-S
Abstract excerpt
Although the involvement of insulin-like signaling in cancer has been well documented in various types of cancers, the association between the genetic variants in the insulin-like signaling and the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) remains unclear. In this study, a total of 498 individuals including 173 HBV related cirrhosis patients, 171 HBV-related HCC patients, and...
Topics
- Adult
- Aged
- Carcinogenesis
- Carcinoma, Hepatocellular
- China
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Hepatitis B virus