Article
High rates of early treatment discontinuation in hepatitis C-infected US veterans.
BMC research notes - 24 Apr 2014
LaFleur Joanne, Hoop Robert, Morgan Timothy, DuVall Scott L, Pandya Prashant, Korner Eli, Knippenberg Kristin, Hayden Candace, Nelson Richard E
Abstract excerpt
BACKGROUND: Patients with chronic hepatitis C (HCV) frequently discontinued dual therapy with pegylated interferon alfa (Peg-IFN) plus ribavirin (RBV) before reaching the recommended duration of 48 or 24 weeks for genotypes (G) 1/4 or 2/3, respectively. We quantified rates of discontinuation despite efficacy (non-LOE) versus lack of efficacy (LOE) versus discontinuation for unknown reasons in a national database...
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