Article
Standard Versus Extended Duration Direct-Acting Antiviral Therapy in Hepatitis C Patients With Slow Response to Treatment.
The Annals of pharmacotherapy - 1 Nov 2020
McKnight Ashley H, Townsend Mary L, Hashem Mohamed G, Naggie Susanna, Park Lawrence P, Britt Rachel B
Abstract excerpt
BACKGROUND: Response-guided hepatitis C therapy was standard with interferon-based regimens but is not used for direct-acting antivirals (DAAs). Week 4 viral kinetics may predict sustained virological response (SVR) with DAAs, but it is unclear whether extending therapy in slow responders affects outcomes. OBJECTIVES: The primary objective was to compare SVR rates between traditional and extended duration groups....
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