Article
An open-safety study of dual antiviral therapy in real-world patients with chronic hepatitis C.
Pharmacoepidemiology and drug safety - 1 Nov 2010
Tinè Fabio, Graviano Domenico, Giannuoli Gandolfo, Madonia Salvatore, Malizia Giuseppe, Patti Salvatore, Fasola Salvatore, Cottone Mario, D'Amico Gennaro
Abstract excerpt
PURPOSE: Treatment of patients with chronic hepatitis C with alpha-interferon and ribavirin usually produces adverse events within the first 3 months. We aimed to assess safety and predictors of discontinuation or dose modification of these drugs. METHODS: Observational study of 312 patients with predominantly genotype 1 chronic hepatitis C treated openly along 5 years in a clinical practice setting. RESULTS:...
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