Article
Gene-gene interaction between CETP and APOE polymorphisms confers higher risk for hypertriglyceridemia in oldest-old Chinese women.
Experimental gerontology - 1 Jul 2014
Sun Liang, Hu Caiyou, Zheng Chenguang, Huang Zezhi, Lv Zeping, Huang Jin, Liang Siying, Shi Xiaohong, Zhu Xiaoquan, Yuan Huiping, Yang Ze
Abstract excerpt
The knowledge of dyslipidemia and its genetic contributors in oldest-old subjects is limited; in addition, the majority of oldest-old subjects are females. Evidence has accumulated that multiple genetic factors play important roles in determining susceptibility to dyslipidemia and extended life span. Cholesterol ester transfer protein (CETP) and apolipoprotein E (APOE) are two plausible candidate genes for human...
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