Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Can Induce Chromosomal Instability through Targeted Degradation of the Mitotic Checkpoint Kinase Bub1

17 Apr 2014

Abstract excerpt

UNLABELLED: Kaposi's sarcoma-associated herpesvirus (KSHV) has a significant contributory role in the development of three major human neoplastic or lymphoproliferative diseases: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). These diseases are associated with chromosomal instability, a hallmark of human cancer. The latency-associated nuclear antigen (LANA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lymphoma Diagnosis and Treatment
Share to Ubiquitin and proteasome pathways
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24741095
DOI: 10.1128/jvi.00554-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Can Induce Chromosomal Instability through Targeted Degradation of the Mitotic Checkpoint Kinase Bub1PMID 24741095Read ↗

Kaposi's Sarcoma-Associated Herpesvirus-Encoded Latency-Associated Nuclear Antigen Induces Chromosomal Instability through Inhibition of p53 FunctionSemantic proximity Read ↗

Kaposi’s Sarcoma-Associated Herpesvirus LANA Hitches a Ride on the ChromosomeSemantic proximity Read ↗

Molecular biology and pathogenesis of Kaposi sarcoma-associated herpesvirusSemantic proximity Read ↗

Cell Cycle Regulatory Functions of the KSHV Oncoprotein LANASemantic proximity Read ↗

The Latency-Associated Nuclear Antigen, a Multifunctional Protein Central to Kaposi‘s Sarcoma-Associated Herpesvirus LatencySemantic proximity Read ↗

Kaposi’s Sarcoma Herpesvirus Genome PersistenceSemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Contributes to Viral Latent Replication by Activating Phosphorylation of SurvivinSemantic proximity Read ↗

Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latencySemantic proximity Read ↗

KSHV Genome Replication and MaintenanceSemantic proximity Read ↗

KSHV LANA—The Master Regulator of KSHV LatencySemantic proximity Read ↗

Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and UbiquitylationSemantic proximity Read ↗

KSHV LANA inhibits TGF-β signaling through epigenetic silencing of the TGF-β type II receptorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.