Article
pix-1 controls early elongation in parallel with mel-11 and let-502 in Caenorhabditis elegans.
PloS one - 1 Jan 2014
Martin Emmanuel, Harel Sharon, Nkengfac Bernard, Hamiche Karim, Neault Mathieu, Jenna Sarah
Abstract excerpt
Cell shape changes are crucial for metazoan development. During Caenorhabditis elegans embryogenesis, epidermal cell shape changes transform ovoid embryos into vermiform larvae. This process is divided into two phases: early and late elongation. Early elongation involves the contraction of filamentous actin bundles by phosphorylated non-muscle myosin in a subset of epidermal (hypodermal) cells. The genes...
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