Article
The effect of trauma-focused therapy on the altered T cell distribution in individuals with PTSD: evidence from a randomized controlled trial.
Journal of psychiatric research - 1 Jul 2014
Morath Julia, Gola Hannah, Sommershof Annette, Hamuni Gilava, Kolassa Stephan, Catani Claudia, Adenauer Hannah, Ruf-Leuschner Martina, Schauer Maggie, Elbert Thomas, Groettrup Marcus, Kolassa Iris-Tatjana
Abstract excerpt
Posttraumatic stress disorder (PTSD) is associated with a reduced ratio of naïve cytotoxic T lymphocytes, an increased ratio of memory cytotoxic T lymphocytes, and a reduced proportion of FoxP3(+) regulatory T lymphocytes. This study investigated whether these immunological alterations are reversible through an evidence-based psychotherapeutic treatment. Therefore, 34 individuals with PTSD were randomly assigned...
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