Article
High LET (56)Fe ion irradiation induces tissue-specific changes in DNA methylation in the mouse.
Environmental and molecular mutagenesis - 1 Apr 2014
Lima Florence, Ding Dacheng, Goetz Wilfried, Yang Austin J, Baulch Janet E
Abstract excerpt
DNA methylation is an epigenetic mechanism that drives phenotype and that can be altered by environmental exposures including radiation. The majority of human radiation exposures occur in a relatively low dose range; however, the biological response to low dose radiation is poorly understood. Based on previous observations, we hypothesized that in vivo changes in DNA methylation would be observed in mice...
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