Article
Diversity in guanosine 3',5'-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants.
The Journal of biological chemistry - 30 May 2014
Nomura Yuhta, Izumi Atsushi, Fukunaga Yoshinori, Kusumi Kensuke, Iba Koh, Watanabe Seiya, Nakahira Yoichi, Weber Andreas P M, Nozawa Akira, Tozawa Yuzuru
Abstract excerpt
The guanosine 3',5'-bisdiphosphate (ppGpp) signaling system is shared by bacteria and plant chloroplasts, but its role in plants has remained unclear. Here we show that guanylate kinase (GK), a key enzyme in guanine nucleotide biosynthesis that catalyzes the conversion of GMP to GDP, is a target of regulation by ppGpp in chloroplasts of rice, pea, and Arabidopsis. Plants have two distinct types of GK that are...
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