Article
Specificity of staphylococcal phage and SaPI DNA packaging as revealed by integrase and terminase mutations.
Molecular microbiology - 1 Apr 2009
Ubeda Carles, Olivarez Nicholas P, Barry Peter, Wang Huaibin, Kong Xiangpeng, Matthews Avery, Tallent Sandra M, Christie Gail E, Novick Richard P
Abstract excerpt
SaPI1 and SaPIbov1 are chromosomal pathogenicity islands in Staphylococcus aureus that carry tst and other superantigen genes. They are induced to excise and replicate by certain phages, are efficiently encapsidated in SaPI-specific small particles composed of phage virion proteins and are transferred at very high frequencies. In this study, we have analysed three SaPI genes that are important for the phage-SaPI...
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