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Article

Investigation of NF-κB1 and NF-κBIA gene polymorphism in non-small cell lung cancer.

BioMed research international - 1 Jan 2014

Oltulu Y M, Coskunpinar E, Ozkan G, Aynaci E, Yildiz P, Isbir T, Yaylim I

Abstract excerpt

Lung cancer is a complex, multifactorial disease which is the leading cause of cancer death in both men and women. NF-κB is a transcription factor which is known to affect the expression of more than 150 genes related to inflammation, lymphocyte activation, cell proliferation, differentiation, and apoptosis, as well as contributing to cell apoptosis and survival. However, NF-κBIA (IκBα) is the inhibitor of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24707489
DOI: 10.1155/2014/530381
PMCID: PMC3953471

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