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Article

The effects of gene polymorphisms in interleukin-4 and interleukin-6 on the susceptibility of rheumatoid arthritis in a Chinese population.

BioMed research international - 1 Jan 2014

Li Xiang, Chai Wei, Ni Ming, Xu Meng, Lian Zijian, Shi Lewis, Bai Yang, Wang Yan

Abstract excerpt

BACKGROUND: Interleukin-4 (IL-4) and interleukin-6 (IL-6) have been reported to associate with pathogenesis of rheumatoid arthritis (RA); however, the role of IL-4 and IL-6 genetic polymorphisms in RA remains unknown. METHOD: A total of 752 unrelated Chinese patients with RA and 798 healthy Chinese volunteers with no family histories of any autoimmune diseases were recruited. The promoter IL-4-590 C/T and...

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Identifiers

PMID: 24707478
DOI: 10.1155/2014/265435
PMCID: PMC3953475

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Source receipt: pubmed, retrieved 7 Sept 2026.

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