Article
Biochemical characterization of sporadic/familial hemiplegic migraine mutations.
Biochimica et biophysica acta - 1 Jul 2014
Weigand Karl M, Swarts Herman G P, Russel Frans G M, Koenderink Jan B
Abstract excerpt
Sporadic hemiplegic migraine type 2 (SHM2) and familial hemiplegic migraine type 2 (FHM2) are rare forms of hemiplegic migraine caused by mutations in the Na(+),K(+)-ATPase α2 gene. Today, more than 70 different mutations have been linked to SHM2/FHM2, randomly dispersed over the gene. For many of these mutations, functional studies have not been performed. Here, we report the functional characterization of nine...
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