Article
Microbial pathogens trigger host DNA double-strand breaks whose abundance is reduced by plant defense responses.
PLoS pathogens - 1 Apr 2014
Song Junqi, Bent Andrew F
Abstract excerpt
Immune responses and DNA damage repair are two fundamental processes that have been characterized extensively, but the links between them remain largely unknown. We report that multiple bacterial, fungal and oomycete plant pathogen species induce double-strand breaks (DSBs) in host plant DNA. DNA damage detected by histone γ-H2AX abundance or DNA comet assays arose hours before the disease-associated necrosis...
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