Article
Runs of homozygosity and a cluster of vulvar cancer in young Australian Aboriginal women.
Gynecologic oncology - 1 Jun 2014
McWhirter Rebekah E, Thomson Russell J, Marthick James R, Rumbold Alice R, Brown Matthew A, Taylor-Thomson Debbie, Maypilama Elaine L, Condon John R, Dickinson Joanne L
Abstract excerpt
OBJECTIVE: A cluster of vulvar cancer exists in young Aboriginal women living in remote communities in Arnhem Land, Australia. A genetic case-control study was undertaken involving 30 cases of invasive vulvar cancer and its precursor lesion, high-grade vulvar intraepithelial neoplasia (VIN), and 61 controls, matched for age and community of residence. It was hypothesized that this small, isolated population may...
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