Article
Investigating a cluster of vulvar cancers in young women: distribution of human papillomavirus and HPV-16 variants in vulvar dysplastic or neoplastic biopsies.
Sexual health - 1 Mar 2013
Tan Sarah E, Garland Suzanne M, Rumbold Alice R, Zardawi Ibrahim, Taylor-Thomson Debbie, Condon John R, Tabrizi Sepehr N
Abstract excerpt
BACKGROUND: A high incidence of vulvar cancer, and its precursor lesion, high-grade vulvar intraepithelial neoplasia (VIN) has been identified in young Indigenous women living in the Arnhem Land region of the Northern Territory (NT) of Australia. This clustering is restricted to women aged <50 years, suggesting that oncogenic human papillomavirus (HPV) is a key causal factor. This study compared the HPV genotype...
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