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Article

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

PloS one - 1 Jan 2014

Diawara Malika R, Hue Christophe, Wilder Steven P, Venteclef Nicolas, Aron-Wisnewsky Judith, Scott James, Clément Karine, Gauguier Dominique, Calderari Sophie

Abstract excerpt

MicroRNAs are emerging as new mediators in the regulation of adipose tissue biology and the development of obesity. An important role of microRNA-125a has been suggested in the pathogenesis of insulin resistance (IR). Here, we characterized the function of microRNA-125a in adipose tissue in a context of experimentally-induced IR and obesity in mice and in obese patients. We showed time dependent overexpression of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24675842
DOI: 10.1371/journal.pone.0091375
PMCID: PMC3967993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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