Article
Disruption of mutated BRAF signaling modulates thyroid cancer phenotype.
BMC research notes - 28 Mar 2014
Hanly Elyse K, Rajoria Shilpi, Darzynkiewicz Zbigniew, Zhao Hong, Suriano Robert, Tuli Neha, George Andrea L, Bednarczyk Robert, Shin Edward J, Geliebter Jan, Tiwari Raj K
Abstract excerpt
BACKGROUND: Thyroid cancer is the most common endocrine-related cancer in the United States and its incidence is rising rapidly. Since among various genetic lesions identified in thyroid cancer, the BRAFV600E mutation is found in 50% of papillary thyroid cancers and 25% of anaplastic thyroid canc...
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