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High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemia

22 Nov 2013

Abstract excerpt

// Ban Xiong Tan 1 , Kian Hoe Khoo 1 , Tit Meng Lim 2 , David Philip Lane 1 1 p53 Laboratory, A-STAR, Singapore 2 Department of Biological Sciences, National University of Singapore, Singapore Correspondence: David P. Lane, email: // Keywords : p53, AML, Mdm4 Received : October 31, 2013 Accepted : November 20, 2013 Published : November 22, 2013 Abstract Although p53 is found mutated in almost 50% of all cancers,...

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PMID: 24659749
DOI: 10.18632/oncotarget.1559

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