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Article

Organoids in cancer research.

Nature reviews. Cancer - 1 Jul 2018

Drost Jarno, Clevers Hans

Abstract excerpt

The recent advances in in vitro 3D culture technologies, such as organoids, have opened new avenues for the development of novel, more physiological human cancer models. Such preclinical models are essential for more efficient translation of basic cancer research into novel treatment regimens for patients with cancer. Wild-type organoids can be grown from embryonic and adult stem cells and display self-organizing...

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PMID: 29692415
DOI: 10.1038/s41568-018-0007-6

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