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Article

Arecoline inhibits epithelial cell viability by upregulating the apoptosis pathway: Implication for oral submucous fibrosis

14 Mar 2014

Abstract excerpt

Oral submucous fibrosis (OSF) is a chronic inflammatory disease characterized by the accumulation of excess collagen, and areca nut chewing has been proposed as a significant etiological factor for disease manifestation. However, the underlying molecular mechanisms regarding areca nut chewing-induced OSF are only partially understood. Herein, we reported that arecoline markedly induced morphologic change in HaCaT...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 24647969
DOI: 10.3892/or.2014.3091

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