Article
Predictive modeling of gingivitis severity and susceptibility via oral microbiota.
The ISME journal - 1 Sept 2014
Huang Shi, Li Rui, Zeng Xiaowei, He Tao, Zhao Helen, Chang Alice, Bo Cunpei, Chen Jie, Yang Fang, Knight Rob, Liu Jiquan, Davis Catherine, Xu Jian
Abstract excerpt
Predictive modeling of human disease based on the microbiota holds great potential yet remains challenging. Here, 50 adults underwent controlled transitions from naturally occurring gingivitis, to healthy gingivae (baseline), and to experimental gingivitis (EG). In diseased plaque microbiota, 27 bacterial genera changed in relative abundance and functional genes including 33 flagellar biosynthesis-related groups...
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